RPL7 Antibody

Code CSB-PA003997
Size US$119
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  • Western Blot analysis of HeLa cells using Ribosomal Protein L7 Polyclonal Antibody
  • Western Blot analysis of customer's(cat sample) using Ribosomal Protein L7 Polyclonal Antibody.
  • Western blot analysis of Mouse-kidney mouse-brain HELA KB SH-SY5Y 293T 3T3 lysis using Ribosomal Protein L7 antibody.
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Product Details

Uniprot No.
Target Names
RPL7
Alternative Names
60S ribosomal protein L7 antibody; humL7 1 antibody; L7 antibody; Ribosomal protein L7 antibody; RL7_HUMAN antibody; RPL 7 antibody; RPL7 antibody; Rpl7a antibody; Surf 3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the C-terminal region of Human Ribosomal Protein L7.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Component of the large ribosomal subunit. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.
Gene References into Functions
  1. HIV-1 Gag NC domain interacts with the ribosomal protein RPL7 endowed with nucleic acid chaperone activity, favoring the notion that RPL7 could be a Gag helper chaperoning factor possibly contributing to the start of Gag assembly PMID: 27515235
  2. In case of L7, importin beta2 or importin beta3 are preferentially used by clusters with a high import efficiency. PMID: 23266416
  3. RPL7 gene expression is decreased in follicular variant of papillary thyroid carcinoma. PMID: 21509594
  4. importin beta3 is essential for the nuclear import of RPL7. The import is mediated via the multifaceted basic amino acid clusters present in the NH(2)-region of RPL7, and is RanGTP-dependent PMID: 20828572
  5. Combining with the phylogenic findings from homologous sequence alignment, the NH2-region of L7, besides being as a eukaryotic expansion segment, can be excluded from building a functional eukaryotic ribosome. PMID: 16797011
  6. L7-endoplasmic reticulum-binding nature could be one of multiple factors that allow a nascent peptide-less ribosome to remain at the endoplasmic reticulum. PMID: 17258209

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Protein Families
Universal ribosomal protein uL30 family
Database Links

HGNC: 10363

OMIM: 604166

KEGG: hsa:6129

STRING: 9606.ENSP00000339795

UniGene: Hs.421257

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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