RPP21 Antibody, Biotin conjugated

Code CSB-PA887986ED01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) RPP21 Polyclonal antibody
Uniprot No.
Target Names
RPP21
Alternative Names
RPP21 antibody; C6orf135 antibody; CAT60 antibody; Ribonuclease P protein subunit p21 antibody; RNaseP protein p21 antibody; EC 3.1.26.5 antibody; Ribonuclease P/MRP 21 kDa subunit antibody; Ribonucleoprotein V antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Ribonuclease P protein subunit p21 protein (2-154AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
Gene References into Functions
  1. Results demonstrate that Rpp29 and Rpp21 depletion impairs double-strand break (DSB) repair by homology-directed repair (HDR), but has no deleterious effect on the integrity of non-homologous end joining. Rpp29 and Rpp21 are rapidly and transiently recruited to laser-microirradiated sites. They bind poly ADP-ribose moieties and are recruited to DNA damage sites in a PARP1-dependent manner. PMID: 28432356
Subcellular Location
Nucleus, nucleolus.
Protein Families
Eukaryotic/archaeal RNase P protein component 4 family
Database Links

HGNC: 21300

OMIM: 612524

KEGG: hsa:79897

STRING: 9606.ENSP00000409799

UniGene: Hs.183232

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