HARS2 Antibody

Code CSB-PA010138HA01HU
Size US$166
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Image
  • Western blot
    All lanes: HARS2 antibody at 2µg/ml + Mouse kidney tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 57, 55 kDa
    Observed band size: 57 kDa

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA010138HA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HARS2 Polyclonal antibody
Uniprot No.
Target Names
HARS2
Alternative Names
4631412B19Rik antibody; AI593507 antibody; HARS related antibody; Hars2 antibody; HARSL antibody; HARSR antibody; HisRS antibody; Histidine translase antibody; Histidine tRNA ligase antibody; Histidine tRNA ligase homolog antibody; Histidine tRNA ligase like antibody; Histidine--tRNA ligase antibody; Histidine--tRNA ligase-like antibody; Histidyl tRNA synthetase 2 antibody; Histidyl tRNA synthetase 2 mitochondrial antibody; Histidyl tRNA synthetase like antibody; HO3 antibody; mitochondrial antibody; Probable histidyl tRNA synthetase mitochondrial antibody; Probable histidyl-tRNA synthetase antibody; SYHM_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Probable histidine--tRNA ligase, mitochondrial protein (34-506AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The HARS2 Antibody (Product code: CSB-PA010138HA01HU) is Non-conjugated. For HARS2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010138HB01HU HARS2 Antibody, HRP conjugated ELISA
FITC CSB-PA010138HC01HU HARS2 Antibody, FITC conjugated
Biotin CSB-PA010138HD01HU HARS2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Mitochondrial aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP).
Gene References into Functions
  1. Mutations in mitochondrial histidyl tRNA synthetase HARS2 cause ovarian dysgenesis and sensorineural hearing loss of Perrault syndrome. PMID: 21464306
  2. This protein has been found differentially expressed in the anterior cingulate cortex in men patients with schizophrenia. PMID: 20381070
Involvement in disease
Perrault syndrome 2 (PRLTS2)
Subcellular Location
Mitochondrion.
Protein Families
Class-II aminoacyl-tRNA synthetase family
Tissue Specificity
A high level expression is seen in the heart, kidney and skeletal muscle while a lower level expression is seen in the brain and liver.
Database Links

HGNC: 4817

OMIM: 600783

KEGG: hsa:23438

STRING: 9606.ENSP00000230771

UniGene: Hs.432560

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