SAMM50 Antibody

Datasheet

Code	CSB-PA896898ESR2HU
Size	US$166
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Image	Western blot All lanes: SAMM50 antibody at 0.98µg/ml Lane 1: Mouse gonadal tissue Lane 2: A375 whole cell lysate Lane 3: A431 whole cell lysate Lane 4: 293T whole cell lysate Lane 5: Hela whole cell lysate Lane 6: A549 whole cell lysate Lane 7: HepG2 whole cell lysate Lane 8: U251 whole cell lysate Lane 9: LO2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA896898ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA896898ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SAMM50 Polyclonal antibody

Uniprot No.

Q9Y512

Target Names

SAMM50

Alternative Names

CGI 51 antibody; CGI-51 antibody; FLJ35825 antibody; FLJ42905 antibody; FLJ99036 antibody; OMP85 antibody; SAM50 antibody; SAM50_HUMAN antibody; Samm50 antibody; sorting and assembly machinery 50kDa antibody; sorting and assembly machinery component 50 homolog (S. cerevisiae) antibody; Sorting and assembly machinery component 50 homolog antibody; sorting and assembly machinery component 50, S. cerevisiae, homolog of antibody; TOB55 antibody; Transformation-related gene 3 protein antibody; TRG-3 antibody; YNL026W antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Sorting and assembly machinery component 50 homolog protein (1-220AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes. Required for the assembly of TOMM40 into the TOM complex.

Gene References into Functions

The authors results demonstrate that SNP in the SAMM50 gene is significantly associated with the presence and severity of NAFLD in a Korean populations. PMID: 29271184
Findings suggest a significant association between variants in COL13A1, ADIPOQ, SAMM50, and PNPLA3, and risk of NAFLD/elevated transaminase levels in Mexican adults with an admixed ancestry. PMID: 29307798
SAMM50 affects the Drp1-dependent mitochondrial morphology. PMID: 27059175
downregulation of SAM50 in BCR-ABL-expressing, but not normal CD34(+) human hematopoietic stem and progenitor cells (HSPCs) caused a significant decrease in growth, colony formation, and replating capacity. PMID: 26855047
the integrity of MICOS and its efficient interaction with Sam50 are indispensable for cristae organization, which is relevant to mitochondrial function. PMID: 26530328
Polymorphisms in the SAMM50 and PARVB genes in addition to those in the PNPLA3 gene were observed to be associated with the development and progression of NAFLD. PMID: 23535911
The study describes a novel role of SAM50 in maintaining the mitochondrial shape and the morphology of cristae. PMID: 22252321

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Subcellular Location

Mitochondrion outer membrane; Multi-pass membrane protein. Cytoplasm. Mitochondrion.

Protein Families

SAM50/omp85 family

Database Links

HGNC: 24276

OMIM: 612058

KEGG: hsa:25813

STRING: 9606.ENSP00000345445

UniGene: Hs.505824

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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