SCAMP2 Antibody

Code CSB-PA020751GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SCAMP2
Alternative Names
SCAMP2; Secretory carrier-associated membrane protein 2; Secretory carrier membrane protein 2
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SCAMP2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.
Gene References into Functions
  1. this finding that SCAMP2 interacts with and regulates the subcellular distribution of both DAT and SERT suggests that interaction with SCAMP2 may constitute an important mechanism for coordinating cell surface expression of monoamine transporters. PMID: 21295544
  2. SCAMP2 plays an important role in the regulation of the subcellular distribution of SERT PMID: 16870614
  3. The strong correlation between SCAMP2 E interactions with PIP2 and inhibition of exocytosis, particularly by SC2-R204A, led us to propose that SCAMP2 interaction with PIP2 within the membrane interface regulates fusion pore formation during exocytosis. PMID: 17713930
  4. SCAMP2 regulates NHE5 transit through recycling endosomes and promotes its surface targeting in an Arf6-dependent manner. PMID: 19276089
Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein.
Protein Families
SCAMP family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 10564

OMIM: 606912

KEGG: hsa:10066

STRING: 9606.ENSP00000268099

UniGene: Hs.458917

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