SENP7 Antibody, HRP conjugated

Datasheet

Code	CSB-PA805340LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SENP7 Polyclonal antibody

Uniprot No.

Q9BQF6

Target Names

SENP7

Alternative Names

KIAA1707 antibody; Senp7 antibody; SENP7_HUMAN antibody; Sentrin specific protease antibody; Sentrin-specific protease 7 antibody; Sentrin/SUMO-specific protease SENP7 antibody; SSP2 antibody; SUMO 1 specific protease 2 antibody; SUMO specific protease antibody; SUMO-1-specific protease 2 antibody; SUMO1/sentrin specific peptidase 7 antibody; SUSP2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Sentrin-specific protease 7 protein (128-366AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.

Gene References into Functions

SPOP inhibits hepatocellular carcinoma (HCC) cell metastasis via ubiquitin-dependent SENP7 proteolysis and may thus serve as a new opinion for the prevention of HCC metastasis. PMID: 29777712
c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4 PMID: 25895136
deSUMOylation by SENP7 is required to promote a permissive chromatin environment for DNA repair. PMID: 24018422
differential splicing of the SENP7 regulates either tumor suppression or progression PMID: 23045645
Loop 1 insertion in SENP6 and SENP7 as a platform to discriminate between SUMO1 and SUMO2/3 isoforms in this subclass of the SUMO protease family. PMID: 21878624
SENP6 and SENP7 exhibit lower rates for processing pre-SUMO1, pre-SUMO2, or pre-SUMO3 in comparison with SENP2 PMID: 18799455

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Protein Families

Peptidase C48 family

Database Links

HGNC: 30402

OMIM: 612846

KEGG: hsa:57337

STRING: 9606.ENSP00000377655

UniGene: Hs.529551

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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