SEPHS1 Antibody

Datasheet

Code	CSB-PA021015ESR2HU
Size	US$166
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Image	Western blot All lanes: SEPHS1 antibody at 3.05μg/ml Lane 1: Mouse liver tissue Lane 2: HepG2 whole cell lysate Lane 3: Mouse kidney tissue Lane 4: U251 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 43, 36 kDa Observed band size: 43 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA021015ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA021015ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SEPHS1 Polyclonal antibody

Uniprot No.

P49903

Target Names

SEPHS1

Alternative Names

SEPHS1 antibody; SELD antibody; SPS antibody; SPS1 antibody; Selenide antibody; water dikinase 1 antibody; EC 2.7.9.3 antibody; Selenium donor protein 1 antibody; Selenophosphate synthase 1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Selenide, water dikinase 1 protein (1-392AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Synthesizes selenophosphate from selenide and ATP.

Gene References into Functions

Three SNPs in SEPSECS and SEPHS1 were found to significantly interact with serum selenium level and Crohn's Disease. PMID: 23112913
Five alternative splice variants of human SPS1 (major type, DeltaE2, DeltaE8, +E9, +E9a) were identified wherein +E9 and +E9a make the same protein. PMID: 20471958
Sps1 affect cell viability upon ionizing radiation via modulation of p53 activity. Sps1 and its product selenophosphate might be involved in cancer prevention in a p53-dependent manner and could be applied to development of a novel cancer therapy. PMID: 16786570

Subcellular Location

[Isoform 1]: Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.

Protein Families

Selenophosphate synthase 1 family, Class II subfamily

Tissue Specificity

[Isoform 1]: Gradually expressed during the cell cycle until G2/M phase and then decreases.; [Isoform 2]: Gradually expressed during the cell cycle until G2/M phase and then decreases.; [Isoform 3]: Gradually expressed during the cell cycle until S phase

Database Links

HGNC: 19685

OMIM: 600902

KEGG: hsa:22929

STRING: 9606.ENSP00000367893

UniGene: Hs.124027

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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