SEPT6 Antibody

1. Results demonstrate that in stored platelets, septine-2 and septin-6 mRNAs have miR- 223 target sites, septin-2 and septin-6 are in complex with Ago-2. The results demonstrate that like in nucleated cells, enucleated platelets also have microRNA-based mechanisms for the regulation of their septins. PMID: 29943706
2. SUMOylation of human septins is critical for septin filament bundling and cytokinesis. PMID: 29051266
3. MiR-223-3p might target gene SEPT6 and promoted the biological behavior of prostate cancer. PMID: 25519054
4. Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis PMID: 25380047
5. The SEPT6 provides the directional guidance cues necessary for polarizing the epithelial microtubule network. PMID: 21788367
6. Data show that Septins of the SEPT6 group preferentially interacted with septins of the SEPT2 group, SEPT3 group and SEPT7 group. PMID: 21082023
7. MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia PMID: 12096348
8. Molecular analysis using rtPCR followed by sequencing confirmed the expression of an MLL-SEPT6 fusion transcript with a novel sequence. PMID: 16843108
9. septin 2, 6, and 7 complexes make up polymerized filaments PMID: 16914550
10. These results indicate that the host proteins hnRNP A1 and septin 6 play important roles in the replication of HCV through RNA-protein and protein-protein interactions. PMID: 17229681
11. crystal structures of the human SEPT2 G domain and the heterotrimeric human SEPT2-SEPT6-SEPT7 complex PMID: 17637674
12. Demonstrate connection between septins/SOCS7/NCK signaling and the DNA damage response. PMID: 17803907
13. co-expression of SEPT12 altered the filamentous structure of SEPT6 in Hela cells PMID: 18047794

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HGNC: 15848

OMIM: 300683

KEGG: hsa:23157

STRING: 9606.ENSP00000341524

UniGene: Hs.496666