SERINC3 Antibody

Datasheet

Code	CSB-PA984539
Size	US$297
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Image	Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/40. Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/40.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SERINC3 Polyclonal antibody

Uniprot No.

Q13530

Target Names

SERINC3

Alternative Names

SERINC3 antibody; DIFF33 antibody; TDE1 antibody; SBBI99 antibody; Serine incorporator 3 antibody; Tumor differentially expressed protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of Human serine incorporator 3

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:50-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm.

Gene References into Functions

SERINC3 and SERINC5 together restricted HIV-1 replication, and this restriction was evaded by Nef PMID: 26416733
TDE1 inhibits apoptosis and stimulates tumorigenesis PMID: 16547497

Subcellular Location

Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.; Cytoplasm, perinuclear region.

Protein Families

TDE1 family

Tissue Specificity

Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.

Database Links

HGNC: 11699

OMIM: 607165

KEGG: hsa:10955

STRING: 9606.ENSP00000255175

UniGene: Hs.272168

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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