SERINC3 Antibody

Datasheet

Code	CSB-PA562640
Size	US$166
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Image	Gel: 8%SDS-PAGE,Lysate: 40 μg,Lane 1-2: Human right lung cancer tissue, Human left lung cancer tissue,Primary antibody: CSB-PA562640(SERINC3 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 minutes
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Product Details
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Target Background

Product Details

Uniprot No.

Q13530

Target Names

SERINC3

Alternative Names

SERINC3 antibody; DIFF33 antibody; TDE1 antibody; SBBI99 antibody; Serine incorporator 3 antibody; Tumor differentially expressed protein 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human SERINC3

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm.

Gene References into Functions

SERINC3 and SERINC5 together restricted HIV-1 replication, and this restriction was evaded by Nef PMID: 26416733
TDE1 inhibits apoptosis and stimulates tumorigenesis PMID: 16547497

Subcellular Location

Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.; Cytoplasm, perinuclear region.

Protein Families

TDE1 family

Tissue Specificity

Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.

Database Links

HGNC: 11699

OMIM: 607165

KEGG: hsa:10955

STRING: 9606.ENSP00000255175

UniGene: Hs.272168

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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