SH3D19 Antibody

Datasheet

Code	CSB-PA711356LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA711356LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA711356LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SH3D19 Polyclonal antibody

Uniprot No.

Q5HYK7

Target Names

SH3D19

Alternative Names

SH3D19 antibody; SH3 domain-containing protein 19 antibody; ADAM-binding protein Eve-1 antibody; EEN-binding protein antibody; EBP antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human SH3 domain-containing protein 19 protein (468-767AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SH3D19 Antibody (Product code: CSB-PA711356LA01HU) is Non-conjugated. For SH3D19 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA711356LB01HU	SH3D19 Antibody, HRP conjugated	ELISA
FITC	CSB-PA711356LC01HU	SH3D19 Antibody, FITC conjugated
Biotin	CSB-PA711356LD01HU	SH3D19 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization.

Gene References into Functions

identified and characterized EBP, a novel EEN binding protein that interacts with the SH3 domain of EEN; normally expressed in cytoplasm but recruited to the nucleus by MLL-EEN [EBP] PMID: 14551139
yeast two-hybrid screening using the cytoplasmic domain of ADAM12 as bait identified a protein designated Eve-1. Eve-1 plays a role in positively regulating the activity of ADAMs in the signaling of EGFR-ligand shedding. PMID: 15280379
occurrence of an unusual TG 3' splice site in intron 6 PMID: 17672918

Subcellular Location

Cytoplasm. Nucleus. Note=Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein.

Tissue Specificity

Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small intestine and lung. Expressed at low levels in colon, thymus, spleen and leukocytes.

Database Links

HGNC: 30418

OMIM: 608674

KEGG: hsa:152503

STRING: 9606.ENSP00000302913

UniGene: Hs.744983

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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