SIK3 Antibody

Code CSB-PA897531ESR2HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA897531ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human thymus tissue using CSB-PA897531ESR2HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) SIK3 Polyclonal antibody
Uniprot No. Q9Y2K2
Target Names SIK3
Alternative Names SIK3 antibody; KIAA0999 antibody; QSK antibody; L19Serine/threonine-protein kinase SIK3 antibody; EC 2.7.11.1 antibody; Salt-inducible kinase 3 antibody; SIK-3 antibody; Serine/threonine-protein kinase QSK antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Serine/threonine-protein kinase SIK3 protein (60-310AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. role in mediating high salt and IL-17 synergy leading to breast cancer cell proliferation PMID: 28658303
  2. Results found that CpG sites of C1orf106, DMBX1, and SIK3 mediate the genetic risk of psoriasis in Chinese Han population. PMID: 27980695
  3. SIK3 is activated in human osteoarthritic cartilage. PMID: 27009967
  4. Developmental role of Sik3 in hearing and requirement for the maintenance of adult auditory function is reported. PMID: 25060954
  5. SIK3 variants were associated with hypertriglyceridemia in Mexicans. PMID: 24886709
  6. These results establish the importance of SIK3 as a mitotic regulator and underscore the potential of SIK3 as a druggable antimitotic target. PMID: 24743732
  7. cAMP-mediated regulation of SIK3 suggest that SIK3 may mediate some of the effects of this important second messenger in adipocytes PMID: 22588126
  8. Overexpression of SIK3 promotes G1/S cell cycle progression, bestows survival advantages to cancer cells for growth and correlates the clinicopathological conditions of patients with ovarian cancer. PMID: 21399663
  9. Fecal ribosomal protein L19 is a genetic prognostic factor for survival in colorectal cancer. PMID: 18266979

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Subcellular Location Cytoplasm
Protein Families Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
Database Links

HGNC: 29165

OMIM: 614776

KEGG: hsa:23387

STRING: 9606.ENSP00000292055

UniGene: Hs.167451

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