SLC33A1 Antibody

Datasheet

Code	CSB-PA291254
Size	US$166
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Image	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: CSB-PA291254(SLC33A1 Antibody) at dilution 1/1100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details
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Target Background

Product Details

Uniprot No.

O00400

Target Names

SLC33A1

Alternative Names

ACATN antibody; ACATN_HUMAN antibody; Acetyl CoA transporter antibody; Acetyl Coenzyme A transporter antibody; Acetyl coenzyme A transporter 1 antibody; Acetyl-CoA transporter 1 antibody; Acetyl-coenzyme A transporter 1 antibody; AT 1 antibody; AT-1 antibody; AT1 antibody; Human Angiotensin II Type 1 Receptor antibody; Slc33a1 antibody; Solute carrier family 33 (acetyl CoA transporter) member 1 antibody; Solute carrier family 33 member 1 antibody; spastic paraplegia 42 (autosomal dominant) antibody; SPG42 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human SLC33A1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:10000
WB	1:1000-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides. Negatively regulates BMP signaling.

Gene References into Functions

results indicate that increased expression of AT-1 can cause an autistic-like phenotype by affecting key neuronal metabolic pathways. PMID: 27242167
SLC33A1 can negatively regulate BMP signaling. PMID: 25402622
Homozygosity mapping displayed a region of commonality among three families at chromosome 3q25. Deep sequencing and conventional sequencing disclosed homozygous or compound heterozygous mutations for all affected subjects in SLC33A1. PMID: 22243965
translocates acetyl-CoA into the ER lumen and is essential for cell viability PMID: 20826464
A missense mutation in SLC33A1 causes autosomal-dominant spastic paraplegia. PMID: 19061983

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Involvement in disease

Spastic paraplegia 42, autosomal dominant (SPG42); Congenital cataracts, hearing loss, and neurodegeneration (CCHLND)

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Families

SLC33A transporter family

Tissue Specificity

Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. With strongest signals in pancreas.

Database Links

HGNC: 95

OMIM: 603690

KEGG: hsa:9197

STRING: 9606.ENSP00000352456

UniGene: Hs.478031

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Phage Display Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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