SLC39A9 Antibody

Code CSB-PA233395
Size US$297
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  • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/20.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SLC39A9 Polyclonal antibody
Uniprot No.
Target Names
SLC39A9
Alternative Names
FLJ11274 antibody; MGC74989 antibody; PRO1377 antibody; S39A9_HUMAN antibody; SLC39A9 antibody; Solute carrier family 39 (zinc transporter), member 9 antibody; Solute carrier family 39 member 9 antibody; UNQ714 antibody; Zinc transporter SLC39A9 antibody; Zinc transporter ZIP9 antibody; ZIP 9 antibody; ZIP-9 antibody; ZIP9 antibody; Zrt- and Irt-like protein 9 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of Human solute carrier family 39, member 9
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May act as a zinc-influx transporter.
Gene References into Functions
  1. The study connects structural features of ZIP9 to its functions and indicates a possible relevance of ZIP9 as a pharmacological target PMID: 28943399
  2. ZIP9 role glioblastoma cells migration.ZIP9 expression affects phosphorylation states of p53 and GSK-3beta. PMID: 27654922
  3. The results show ZIP9 is a specific Gi coupled-mAR mediating testosterone-induced MAP kinase and zinc signaling in PC3-ZIP9 cells. PMID: 28219737
  4. ZIP9 expression in glioma tumors was not associated with tumor grade or IDH1 mutation status. PMID: 25921144
  5. ZIP9 mediates testosterone promotion of apoptosis and is widely expressed in human tissues and up-regulated in malignant breast and prostate tissues, suggesting that it is a potential therapeutic target for treating breast and prostate cancers. PMID: 25014355
  6. SLC39A9 functions to regulate zinc homeostasis in the secretory pathway without significantly altering cytosolic zinc homeostasis. PMID: 19420709

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
ZIP transporter (TC 2.A.5) family
Database Links

HGNC: 20182

KEGG: hsa:55334

STRING: 9606.ENSP00000336887

UniGene: Hs.432690

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