SLC44A1 Antibody

1. SLC44A1 and KLF13 may be involved in tumorigenesis and the metastasis of colon cancer by miRNA regulation PMID: 29408621
2. The differential expression pattern of CTL1 and CTL2 suggests that CTL1 is the key transporter involved in choline transport from maternal circulation and both transporters are likely involved in stromal and endothelial cell choline transport. PMID: 26601765
3. This study showed that SLC44A1-PRKCA fusion seems to be a specific characteristic of Papillary glioneuronal tumors with a high diagnostic value. PMID: 26671581
4. Reduced CTL1 expression is associated with postural orthostatic tachycardia syndrome. PMID: 25466896
5. NCI-H69 cells express the choline transporter CTL1 which uses a directed H(+) gradient as a driving force, and its transport functions in co-operation with NHE1. PMID: 23948665
6. REVIEW highlights discovery and characterization of SLC44A1, describes its expression patterns and subcellular localization and summarizes evidence for the role of this choline transporter in the central nervous system. PMID: 22483272
7. CTL1 is expressed in both SH-SY5Y and LA-N-2 cells and is responsible for choline uptake that relies on a directed hydrogen ion gradient as a driving force. PMID: 21185344
8. In conclusion, choline transport in A549 cells is increased by treatment with DEX, and the increase is mediated by induction of functional choline transporters CTL1 and CTL2. PMID: 20410607
9. This study provides the first example of CHT1 expression in neurons which do not use acetylcholine as neurotransmitter. PMID: 15691711
10. Data suggest that an impaired choline transporter-like protein-1 trafficking is the key contributing factor to reduced choline uptake, subsequent to the PMA-induced THP-1 differentiation to macrophages. PMID: 16319125
11. characterization the 5'-flanking region of the human (h)CTL1 gene and some of the possible mechanisms of its regulation, including promoter activity, splicing, and expression PMID: 16609143
12. SLC44A1 mRNA and protein expression were down-regulated during choline deficiency. PMID: 19357133
13. The presence of CTL1 protein in rat and human CNS regions, where it is found in neuronal, glial and endothelial cells, suggests that malfunction of this transporter could have important implications in nervous system development and repair. PMID: 19519661

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HGNC: 18798

OMIM: 606105

KEGG: hsa:23446

STRING: 9606.ENSP00000363852

UniGene: Hs.573495