SLC6A13 Antibody

Datasheet

Code	CSB-PA889104LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: K562 whole cell lysate(30µg), Raji whole cell lysate(30µg), 786-O whole cell lysate(30µg), Mouse Brain tissue lysate(20µg),Mouse Kidney tissue lysate(20µg),Rat Brain tissue lysate(20µg) All lanes: SLC6A13 antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/20000 dilution Predicted band size: 69,58,11 kDa Observed band size: 58 kDa Exposure time: 120s Immunofluorescence staining of Hela cell with CSB-PA889104LA01HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). Immunofluorescence staining of Hela cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC6A13 Polyclonal antibody

Uniprot No.

Q9NSD5

Target Names

SLC6A13

Alternative Names

GABA transport protein antibody; GAT 2 antibody; GAT-2 antibody; GAT2 antibody; S6A13_HUMAN antibody; SLC6A13 antibody; Sodium- and chloride-dependent GABA transporter 2 antibody; Solute carrier family 6 (Neurotransmitter transporter, GABA), member 13 antibody; Solute carrier family 6 member 13 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Sodium- and chloride-dependent GABA transporter 2 protein

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Form

Liquid

Tested Applications

ELISA, WB,IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

CUSABIO is glad to provide a highly specific antibody directed against an epitope of human SLC6A13. The antibody (CSB-PA889104LA01HU) is produced in the rabbit against a peptide corresponding to amino acid residues 1-40 of human SLC6A13. It exists as an unconjugated IgG isotype. Its purity is over 95% using protein G purified. This SLC6A13 antibody can be used in ELISA, WB, IHC, and IF analyses. And it has been designed to recognize SLC6A13 from mouse and human samples. Its target protein SLC6A13 is mainly expressed in the hepatocytes and is the major taurine transporter in the liver.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Sodium-dependent GABA and taurine transporter. In presynaptic terminals, regulates GABA signaling termination through GABA uptake. May also be involved in beta-alanine transport.

Gene References into Functions

Results suggest that gamma-aminobutyric acid transporter 2 GAT-2 is a high selectivity/low affinity transporter. PMID: 22932902

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A13 subfamily

Tissue Specificity

Expressed in brain, kidney, lung, liver and testis.

Database Links

HGNC: 11046

OMIM: 615097

KEGG: hsa:6540

STRING: 9606.ENSP00000339260

UniGene: Hs.504398

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Email: [email protected]
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Gene Synthesis Service

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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