SLC7A3 Antibody, HRP conjugated

Datasheet

Code	CSB-PA855505LB01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SLC7A3 Polyclonal antibody

Uniprot No.

Q8WY07

Target Names

SLC7A3

Alternative Names

SLC7A3 antibody; ATRC3 antibody; CAT3 antibody; Cationic amino acid transporter 3 antibody; CAT-3 antibody; CAT3 antibody; Cationic amino acid transporter y+ antibody; Solute carrier family 7 member 3 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cationic amino acid transporter 3 protein (428-475AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner.

Gene References into Functions

rare hypomorphic variants of SLC7A3 exist in male individuals, SLC7A3 variants possibly contribute to the etiology of autism spectrum disorders in male subjects in association with other genetic factors PMID: 26215737
knockdown impaired AMPK-PPAR-alpha signaling and resulted in lipid accumulation under glucose starvation in liver cells PMID: 25130427
CAT1, CAT2, and CAT3 localized in adult brains but with uneven distribution. PMID: 22870827
is concluded that hCAT-3 is a passive transport system that conducts monovalent cations including L-Arg. PMID: 15737334
It is concluded that similar to hCAT-1, hCAT-3 activity is decreased by PKC via reduction of transporter molecules in the plasma membrane. PMID: 16332251

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Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

Amino acid-polyamine-organocation (APC) superfamily, Cationic amino acid transporter (CAT) (TC 2.A.3.3) family

Tissue Specificity

Highly expressed in thymus, uterus and testis. Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen. In brain, highest expression in thalamus, hippocampus and amygdala.

Database Links

HGNC: 11061

OMIM: 300443

KEGG: hsa:84889

STRING: 9606.ENSP00000298085

UniGene: Hs.175220

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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