SLC9A7 Antibody

Datasheet

Code	CSB-PA934421
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA934421(SLC9A7 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Target Background

Product Details

Uniprot No.

Q96T83

Target Names

SLC9A7

Alternative Names

Na(+)/H(+) exchanger 7 antibody; NHE-7 antibody; NHE7 antibody; Nonselective sodium potassium/proton exchanger antibody; SL9A7_HUMAN antibody; SLC9A6 antibody; SLC9A7 antibody; Sodium/hydrogen exchanger 7 antibody; Solute carrier family 9 (sodium/hydrogen exchanger), member 7 antibody; Solute carrier family 9 member 7 antibody; Solute carrier family 9, isoform 7 antibody; Solute carrier family 9, member 7 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human SLC9A7

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to the regulation of Golgi apparatus volume and pH.

Gene References into Functions

In a Saudi Arabian cohort of patients with cystinuria, two new variants in the SLC3A1 and SLC9A7 genes were discovered. All of the detected mutations were missense variants in three different exons, such as c.1711 T > A (p.Cys571Ser) (exon 10), c.1166C > T p.Thr389Met (exon 11) and c.1400 T > A p.Met467Lys (exon 8). PMID: 28166740
NHE7 mediates an acidification of intracellular vesicles that is additive to that of V-ATPases and that accelerates endocytosis. PMID: 24767989
these results suggest that NHE7 enhances tumor progression. PMID: 22076128
This review defines NHE6-9 as organellar NHEs that are fairly dynamic, implying that they are subjected to intracellular trafficking and thus they continuously shuttle between organelles and the plasma membrane. PMID: 21171650
The results suggest that two membrane proximal regions (residues 533-559 and 563-568) play an important role in targeting NHE7 to the TGN PMID: 20364249
Secretory carrier membrane proteins participate in the shuttling of NHE7 between recycling vesicles and the TGN PMID: 15840657
Among the NHE7-binding proteins identified, CD44, a cell surface glycoprotein receptor for hyaluronate and other ligands, showed regulated interaction with NHE7. PMID: 18654930

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Subcellular Location

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Protein Families

Monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family

Tissue Specificity

Ubiquitously expressed.

Database Links

HGNC: 17123

OMIM: 300368

KEGG: hsa:84679

STRING: 9606.ENSP00000330320

UniGene: Hs.91389

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Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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