SMIM1 Antibody

Code CSB-PA450720LA01HU
Size US$166
Order now
Image
  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA450720LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA450720LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SMIM1 Polyclonal antibody
Uniprot No.
Target Names
SMIM1
Alternative Names
Small integral membrane protein 1 antibody; SMIM1 antibody; SMIM1_HUMAN antibody; Vel blood group antigen antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Small integral membrane protein 1 protein (1-46AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SMIM1 Antibody (Product code: CSB-PA450720LA01HU) is Non-conjugated. For SMIM1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA450720LB01HU SMIM1 Antibody, HRP conjugated ELISA
FITC CSB-PA450720LC01HU SMIM1 Antibody, FITC conjugated
Biotin CSB-PA450720LD01HU SMIM1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews
Average Rating:
5.0 - 2 reviews

Submit a Review here

Applications : Immunohistochemical staining

Sample type: Cells

Review: Analysis for SMIM1 and ANXA7 expression in a cohort of LC, HCC and HC, respectively. The protein expression was calculated from mass spectrometry data and the signifi cant difference analysis were conducted between groups; E- F, The expression trend of SMIM1 and ANXA7 during the tumorigenesis were verifi ed with PRM strategy with another batch of clinical samples from LC (N=9), HCC (N=11) and HC (N=10); G. Immunostaining for SMIM1 in normal liver and HCC tissue.

By Anonymous

Applications : Immunohistochemistry

Sample type: cells

Review: Alterations in RBCs and potential biomarker identification during tumorigenesis of LC to HCC. Immunostaining of SMIM1 in normal liver and HCC tissue. Immunostaining of SMIM1 in normal liver and HCC tissue.

By Anonymous

Target Background

Function
Regulator of red blood cell formation.
Gene References into Functions
  1. rs1175550G and to a lesser extent rs143702418C independently increase SMIM1 and Vel antigen expression. PMID: 28084402
  2. Among the 448 samples analysed, 10 (2.23%) harboured the 17 bp deletion of the gene SMIM1, and all were heterozygote for the SMIM1*64_80 del allele. PMID: 27328373
  3. Alleles that initially entered the population have been maintained within the population. The c.64_80del null allele of SMIM1 is one such allele, thus having implications for transfusion medicine and child or maternal health. PMID: 26666208
  4. SMIM1 carries the Vel antigen as a type II membrane protein with a predicted C-terminal extracellular domain of only 3-12 amino acids PMID: 26452714
  5. Weak Vel expression levels are caused by multiple genetic factors in SMIM1 and probably also by other genetic or environmental factors. PMID: 25647324
  6. A cohort of 70 Vel- individuals was found to be uniformly homozygous for a 17 nucleotide deletion in the coding sequence of SMIM1. PMID: 23505126
  7. Loss of SMIM1 is associated with reduction in red blood cell formation. PMID: 23563606
  8. Loss of SMIM1 is associated with reduction in red blood cell formation. PMID: 23563608

Show More

Hide All

Subcellular Location
Cell membrane; Single-pass type II membrane protein.
Protein Families
SMIM1 family
Tissue Specificity
Highly expressed in the bone marrow and expressed at lower levels in non-hematopoietic tissues. Highly expressed in erythroleukemia cell lines. Up-regulated in CD34+ hematopoietic progenitors cultured toward red blood cells.
Database Links

HGNC: 44204

OMIM: 615242

KEGG: hsa:388588

STRING: 9606.ENSP00000457386

UniGene: Hs.22047

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
webinars: DT3C facilitates antibody internalization X
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*