SH3GLB2 Antibody

Code CSB-PA868296LA01HU
Size US$166
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  • Western blot
    All lanes: SH3GLB2 antibody at 1µg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: Mouse gonadal tissue
    Lane 3: Mouse lung tissue
    Lane 4: U87 whole cell lysate
    Lane 5: THP-1 whole cell lysate
    Lane 6: A549 whole cell lysate
    Lane 7: MCF-7 whole cell lysate
    Lane 8: Mouse liver tissue
    Lane 9: A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 44, 45 kDa
    Observed band size: 44 kDa

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA868296LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SH3GLB2 Polyclonal antibody
Uniprot No.
Target Names
SH3GLB2
Alternative Names
Endophilin B2 antibody; Endophilin-B2 antibody; OTTHUMP00000022320 antibody; PP6569 antibody; PP9455 antibody; Retinoid receptor induced gene 1 antibody; RRIG1 antibody; SH3 containing protein SH3GLB2 antibody; SH3 domain GRB2 like endophilin B2 antibody; SH3 domain-containing GRB2-like protein B2 antibody; SH3GLB2 antibody; SHLB2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Endophilin-B2 protein (1-395AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SH3GLB2 Antibody (Product code: CSB-PA868296LA01HU) is Non-conjugated. For SH3GLB2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA868296LB01HU SH3GLB2 Antibody, HRP conjugated ELISA
FITC CSB-PA868296LC01HU SH3GLB2 Antibody, FITC conjugated
Biotin CSB-PA868296LD01HU SH3GLB2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. Here the authors report that Endophilin B2, similarly to Endophilin B1, plays an indispensable role in mitochondria sequestration and inner mitochondrial membrane (IMM) protein degradation during mitophagy. PMID: 27112121
  2. Data (including data from studies in knockout mice) suggest that SH3GLB2 regulates trafficking of endocytic vesicles and autophagosomes to late endosomes or lysosomes; despite having an intracellular localization and tissue distribution similar to endophilin B1, endophilin B2 is dispensable for mitochondrial apoptosis. PMID: 28455444
  3. the potential importance of the endophilin B2-plectin complex in the biological functions depending on nuclear migration and positioning. PMID: 23921385
  4. identified a nonmutated HLA-A2-binding epitope in the human ortholog SH3GLB2, which primed T cells from healthy HLA-A2(+) individuals PMID: 18303116
Subcellular Location
Cytoplasm.
Protein Families
Endophilin family
Tissue Specificity
Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.
Database Links

HGNC: 10834

OMIM: 609288

KEGG: hsa:56904

STRING: 9606.ENSP00000361640

UniGene: Hs.460238

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