SH3GLB2 Antibody

Datasheet

Code	CSB-PA868296LA01HU
Size	US$166
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Image	Western blot All lanes: SH3GLB2 antibody at 1µg/ml Lane 1: Hela whole cell lysate Lane 2: Mouse gonadal tissue Lane 3: Mouse lung tissue Lane 4: U87 whole cell lysate Lane 5: THP-1 whole cell lysate Lane 6: A549 whole cell lysate Lane 7: MCF-7 whole cell lysate Lane 8: Mouse liver tissue Lane 9: A431 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 44, 45 kDa Observed band size: 44 kDa Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA868296LA01HU at dilution of 1:100
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SH3GLB2 Polyclonal antibody

Uniprot No.

Q9NR46

Target Names

SH3GLB2

Alternative Names

Endophilin B2 antibody; Endophilin-B2 antibody; OTTHUMP00000022320 antibody; PP6569 antibody; PP9455 antibody; Retinoid receptor induced gene 1 antibody; RRIG1 antibody; SH3 containing protein SH3GLB2 antibody; SH3 domain GRB2 like endophilin B2 antibody; SH3 domain-containing GRB2-like protein B2 antibody; SH3GLB2 antibody; SHLB2_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Endophilin-B2 protein (1-395AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SH3GLB2 Antibody (Product code: CSB-PA868296LA01HU) is Non-conjugated. For SH3GLB2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA868296LB01HU	SH3GLB2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA868296LC01HU	SH3GLB2 Antibody, FITC conjugated
Biotin	CSB-PA868296LD01HU	SH3GLB2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Gene References into Functions

Here the authors report that Endophilin B2, similarly to Endophilin B1, plays an indispensable role in mitochondria sequestration and inner mitochondrial membrane (IMM) protein degradation during mitophagy. PMID: 27112121
Data (including data from studies in knockout mice) suggest that SH3GLB2 regulates trafficking of endocytic vesicles and autophagosomes to late endosomes or lysosomes; despite having an intracellular localization and tissue distribution similar to endophilin B1, endophilin B2 is dispensable for mitochondrial apoptosis. PMID: 28455444
the potential importance of the endophilin B2-plectin complex in the biological functions depending on nuclear migration and positioning. PMID: 23921385
identified a nonmutated HLA-A2-binding epitope in the human ortholog SH3GLB2, which primed T cells from healthy HLA-A2(+) individuals PMID: 18303116

Subcellular Location

Cytoplasm.

Protein Families

Endophilin family

Tissue Specificity

Detected in skeletal muscle, adipocyte, brain, lung, colon and mammary gland.

Database Links

HGNC: 10834

OMIM: 609288

KEGG: hsa:56904

STRING: 9606.ENSP00000361640

UniGene: Hs.460238

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Endocytosis

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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