SRFBP1 Antibody, HRP conjugated

Datasheet

Code	CSB-PA839864LB01HU
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SRFBP1 Polyclonal antibody

Uniprot No.

Q8NEF9

Target Names

SRFBP1

Alternative Names

p49 / STRAP antibody; p49 antibody; p49/STRAP antibody; serum response factor binding protein 1 antibody; Serum response factor-binding protein 1 antibody; SRF dependent transcription regulation associated protein antibody; SRF-dependent transcription regulation-associated protein antibody; SRFB1_HUMAN antibody; SRFBP 1 antibody; SRFBP1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Serum response factor-binding protein 1 protein (201-429AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

Gene References into Functions

P49/STRAP expression was increased in the old versus young adult mouse hearts and also increased with advancing population doubling levels in cultured human umbilical vein endothelial cells. The increased expression of p49/STRAP in late life may alter the status of histone acetylation and impact mitochondrial dynamics and thereby reduce mitochondrial function and cardiac performance during mammalian senescence. PMID: 27337995
SRFBP1 is an HCV-specific, pan-genotypic host entry factor. PMID: 26212323
p49/STRAP may be an important SRF cofactor in the transcriptional regulation of mammalian cardiac muscle genes throughout the life span PMID: 15492011
p49/STRAP plays a role in the regulation of intracellular processes such as cardiac cellular metabolism, gene expression, and possibly aging. PMID: 18230186
p49/STRAP can be considered a bona fide co-chaperone of Hsp70. PMID: 19751705

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Subcellular Location

Cytoplasm, perinuclear region.

Tissue Specificity

Abundantly expressed in heart and skeletal muscle, and at much lower levels in brain and lung.

Database Links

HGNC: 26333

OMIM: 610479

KEGG: hsa:153443

STRING: 9606.ENSP00000341324

UniGene: Hs.107622

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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