SRPRB Antibody

Datasheet

Code	CSB-PA896911LA01HU
Size	US$166
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Image	Western blot All lanes: SRPRB antibody at 2μg/ml Lane 1: HepG2 whole cell lysate Lane 2: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30 kDa Observed band size: 30 kDa Immunofluorescent analysis of Hela cells using CSB-PA896911LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SRPRB Polyclonal antibody

Uniprot No.

Q9Y5M8

Target Names

SRPRB

Alternative Names

SRPRB; PSEC0230; Signal recognition particle receptor subunit beta; SR-beta; Protein APMCF1

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Signal recognition particle receptor subunit beta protein (58-271AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SRPRB Antibody (Product code: CSB-PA896911LA01HU) is Non-conjugated. For SRPRB Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA896911LB01HU	SRPRB Antibody, HRP conjugated	ELISA
FITC	CSB-PA896911LC01HU	SRPRB Antibody, FITC conjugated
Biotin	CSB-PA896911LD01HU	SRPRB Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.

Gene References into Functions

Results show that SRPRB promotes cell apoptosis through NF-kappaB activation. Its expression is regulated by SERP1 in pancreatic ductal adenocarcinoma. PMID: 28902358
APMCF1 may be the gene coding human signal recognition particle receptor beta and belongs to the small-G protein superfamily. Its strong expression pattern in colon cancer suggests it may play a role in colon cancer development. PMID: 12918107
APMCF1 participates at least partially in cell cycle regulation through regulating genes such as p21 and TIMP3. PMID: 17080297

Subcellular Location

Endoplasmic reticulum membrane; Single-pass membrane protein.

Protein Families

SRP receptor beta subunit family

Database Links

HGNC: 24085

OMIM: 616883

KEGG: hsa:58477

STRING: 9606.ENSP00000418401

UniGene: Hs.12152

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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