SRSF4 Antibody

Datasheet

Code	CSB-PA021156ESR2HU
Size	US$166
	Order now
Image	Western blot All lanes: SRSF4 antibody at 4µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 57 kDa Observed band size: 57 kDa Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA021156ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA021156ESR2HU at dilution of 1:100
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SRSF4 Polyclonal antibody

Uniprot No.

Q08170

Target Names

SRSF4

Alternative Names

arginine/serine-rich 4 antibody; Pre mRNA splicing factor SRP75 antibody; Pre-mRNA-splicing factor SRP75 antibody; Serine/arginine-rich splicing factor 4 antibody; Splicing factor antibody; Splicing factor, arginine/serine rich 4 antibody; Splicing factor, arginine/serine rich, 75-KD antibody; SRP001LB antibody; SRP75 antibody; Srsf4 antibody; SRSF4_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Serine/arginine-rich splicing factor 4 protein (1-180AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:200-1:1000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The polyclonal antibody against SRSF4 was synthesized in rabbits that were immunized with the recombinant human SRSF4 (1-180aa). The antibody was subsequently isolated and underwent antigen affinity purification. It shows exclusive reactivity with human SRSF4 protein.

The SRSF4 antibody has been validated for use in ELISA, WB, and IHC applications. This antibody can thus be used for localization and qualitative or quantitative evaluation of the SRSF4 protein. SRSF4 protein mainly helps to promote efficient splicing of the pre-mRNA into the correct mRNA isoform. It is also implicated in other cellular processes, such as mRNA export from the nucleus to the cytoplasm, translation initiation, and mRNA stability.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.

Gene References into Functions

Review of the role of serine and arginine rich splicing factor 4 (SRSF4) in physiology, gene expression regulation and disease. PMID: 29789787
Many of the splicing alterations induced by cisplatin are caused by SRSF4 and they contribute to apoptosis in a process requires class I PI3K. PMID: 25884497
SRp75 inhibits splicing of tau exon 10 by binding to the CA repeat in the intronic splicing silencer downstream of the exon, and requires hnRNPG to exert its full regulatory effect on tau exon 10. PMID: 21723381
Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3. PMID: 20685659
the c.1002-1110_1113delTAAG mutation creates a new intronic splicing regulatory element in intron 6b of the CFTR gene exclusively recognized by SRp75 PMID: 19759008

Hide All

Subcellular Location

Nucleus speckle.

Protein Families

Splicing factor SR family

Database Links

HGNC: 10786

OMIM: 601940

KEGG: hsa:6429

STRING: 9606.ENSP00000362900

UniGene: Hs.469970

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address