ST6GALNAC6 Antibody

Code CSB-PA850251LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA850251LA01HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ST6GALNAC6 Polyclonal antibody
Uniprot No. Q969X2
Target Names ST6GALNAC6
Alternative Names ST6GALNAC6 antibody; SIAT7F antibody; UNQ708/PRO1359 antibody; Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 antibody; EC 2.4.99.- antibody; GalNAc alpha-2,6-sialyltransferase VI antibody; ST6GalNAc VI antibody; ST6GalNAcVI antibody; hST6GalNAc VI antibody; Sialyltransferase 7F antibody; SIAT7-F antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 protein (65-333AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in normal and malignant kidney. Participates in the synthesis of disialyl Lewis a (Le(a)).
Gene References into Functions
  1. novel substrate specificity of ST6GalNAc VI, which is responsible for the synthesis of disialyl Lea but not for alpha-series gangliosides in human colon tissues PMID: 12668675
  2. ST6GalNAc-VI and disialylgalactosylgloboside were found in proximal tubule epithelial cells in normal kidney tissues PMID: 17123352
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 29 family
Tissue Specificity Expressed in kidney, in proximal tubule epithelial cells. Expressed in colon cell lines.
Database Links

HGNC: 23364

OMIM: 610135

KEGG: hsa:30815

STRING: 9606.ENSP00000291839

UniGene: Hs.109672

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