STAC3 Antibody

Datasheet

Code	CSB-PA839373LA01HU
Size	US$166
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Image	Western blot All lanes: STAC3 antibody at 12µg/ml + Rat lung tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 42, 38, 21 kDa Observed band size: 42 kDa
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Product Details
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Target Background

Product Details

Uniprot No.

Q96MF2

Alternative Names

MGC2793 antibody; SH3 and cysteine rich domain 3 antibody; SH3 and cysteine rich domain-containing protein 3 antibody; SH3 and cysteine-rich domain-containing protein 3 antibody; stac3 antibody; STAC3_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Rat

Immunogen

Recombinant Human SH3 and cysteine-rich domain-containing protein 3 protein (1-253AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The STAC3 Antibody (Product code: CSB-PA839373LA01HU) is Non-conjugated. For STAC3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA839373LB01HU	STAC3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA839373LC01HU	STAC3 Antibody, FITC conjugated
Biotin	CSB-PA839373LD01HU	STAC3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane. Slows down the inactivation rate of the calcium channel CACNA1C.

Gene References into Functions

STAC3 mutation is associated with overlapping features of Carey-Fineman-Ziter syndrome and Moebius syndrome. PMID: 28777491
A mutation in human STAC3 is the genetic basis of the debilitating Native American myopathy. PMID: 23736855

Involvement in disease

Native American myopathy (NAM)

Subcellular Location

Cytoplasm. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma, T-tubule.

Database Links

HGNC: 28423

OMIM: 255995

KEGG: hsa:246329

STRING: 9606.ENSP00000329200

UniGene: Hs.417595

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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