STAU2 Antibody

1. during genotoxic stress, Stau2 is downregulated at the promoter level in an ATR- and E2F1-dependent manner, leading to increased levels of DNA damage and apoptosis. PMID: 26843428
2. Authors establish that human Staufen-2, a host factor which is up-regulated upon HIV-1 infection, interacts with HIV-1 Rev, thereby promoting its RNA export activity and progeny virus formation. PMID: 24520823
3. Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity. PMID: 23263869
4. We suggest a role for Stau2 in the generation and regulation of Map1b mRNA containing granules that are required for mGluR-long-term depression PMID: 21508097
5. Data show that Stau2 is localized to the neuronal soma and dendrites, but it does not colocalize with Stau1-containing particles. PMID: 12140260
6. Stau1- and Stau2-mRNPs associate with distinct but overlapping sets of cellular mRNAs. PMID: 18094122

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HGNC: 11371

OMIM: 605920

KEGG: hsa:27067

STRING: 9606.ENSP00000428756

UniGene: Hs.561815