STK16 Antibody

Code CSB-PA022835ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: STK16 antibody at 12μg/ml
    Lane 1: A549 whole cell lysate
    Lane 2: Mouse brain tissue
    Lane 3: A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 35 kDa
    Observed band size: 35 kDa

  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA022835ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA022835ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) STK16 Polyclonal antibody
Uniprot No.
Target Names
STK16
Alternative Names
EDPK antibody; F52 antibody; FLJ39635 antibody; hPSK antibody; KRCT antibody; MGC16211 antibody; MPSK antibody; MPSK1 antibody; Myristoylated and palmitoylated serine/threonine protein kinase antibody; Myristoylated and palmitoylated serine/threonine-protein kinase antibody; PKL12 antibody; Protein kinase expressed in day 12 fetal liver antibody; Protein kinase Krct antibody; Protein kinase PKL12 antibody; Serine/threonine kinase 16 antibody; Serine/threonine protein kinase 16 antibody; Serine/threonine-protein kinase 16 antibody; Stk16 antibody; STK16_HUMAN antibody; TGF beta stimulated factor 1 antibody; TGF-beta-stimulated factor 1 antibody; TGFB stimulated factor 1 antibody; Transforming growth factor beta stimulated factor 1 antibody; TSF-1 antibody; TSF1 antibody; Tyrosine protein kinase STK16 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Serine/threonine-protein kinase 16 protein (1-305AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:200-1:1000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
Gene References into Functions
  1. we revealed STK16 as a novel actin binding protein that resides in the Golgi, which regulates actin dynamics to control Golgi structure and participate in cell cycle progression. PMID: 28294156
  2. MAL2 and STK16 function to sort secretory soluble cargo into the constitutive secretory pathway in hepatocytes. PMID: 25084525
  3. The Endogenous STK16 subcellular localization was evaluated by indirect immunofluorescence in NRK cells, demonstrating a Golgi-associated pattern that appears to be independent of signals provided by integrin pathways. PMID: 16310770
Subcellular Location
Cytoplasm, perinuclear region. Membrane; Lipid-anchor.
Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Tissue Specificity
Ubiquitously expressed at very low levels.
Database Links

HGNC: 11394

OMIM: 604719

KEGG: hsa:8576

STRING: 9606.ENSP00000379964

UniGene: Hs.153003

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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