STMN3 Antibody

Code CSB-PA004184
Size US$100
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  • Western Blot analysis of 293 cells using Stathmin-3 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
STMN3
Alternative Names
AI604839 antibody; R75323 antibody; RP23-83A14.1 antibody; SCG10-like protein antibody; Scgn10 like protein antibody; Sclip antibody; Stathmin like 3 antibody; Stathmin-3 antibody; STMN3 antibody; STMN3_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human Stathmin-3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.
Gene References into Functions
  1. our findings demonstrate that SCLIP plays an important role in glioma pathology, and may represent a novel therapeutic strategy against human glioma. PMID: 25511414
  2. Overexpression of ID1 in two different cell lines induced STMN3 and GSPT1 at the transcriptional level, while depletion of ID1 reduced their expression. PMID: 25028095
  3. We found that reduced expression and possibly posttranslational modification of SCLIP following paclitaxel treatment impaired the microtubule-destabilizing effect of SCLIP PMID: 23543364
  4. Specific serine-proline phosphorylation and glycogen synthase kinase 3beta-directed subcellular targeting of stathmin 3/Sclip in neurons PMID: 22577147
  5. Studies suggest that a STAT3-SCLIP interaction is required to preserve SCLIP stability and contributes to the maintenance of normal epithelial morphology. PMID: 19824884
  6. The substantial expression of SCLIP in most tissues points out a novel function outside the nervous system and raises the possibility that its coexpression with stathmin could provide some degree of functional redundancy. PMID: 12676564

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Subcellular Location
Golgi apparatus. Cell projection, growth cone. Cell projection, axon. Cytoplasm, cytosol.
Protein Families
Stathmin family
Tissue Specificity
Neuron specific.
Database Links

HGNC: 15926

OMIM: 608362

KEGG: hsa:50861

STRING: 9606.ENSP00000359070

UniGene: Hs.639609

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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