STYX Antibody

Code CSB-PA851966LA01HU
Size US$299
Image
  • Western Blot
    Positive WB detected in: MCF-7 whole cell lysate, 293T whole cell lysate, HL60 whole cell lysate
    All lanes: STYX antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 26 kDa
    Observed band size: 26 kDa
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) STYX Polyclonal antibody
Uniprot No. Q8WUJ0
Target Names STYX
Alternative Names Protein tyrosine phosphatase like protein antibody; Protein tyrosine phosphatase-like protein antibody; Serine/threonine/tyrosine interacting protein antibody; Serine/threonine/tyrosine-interacting protein antibody; Styx antibody; STYX_HUMAN antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Serine/threonine/tyrosine-interacting protein (1-223AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Catalytically inactive phosphatase. Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2). Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2). Seems to play a role in spermiogenesis (By similarity).
Gene References into Functions
  1. The authors show that STYX binds to the F-box domain of FBXW7 and disables its recruitment into the SCF ubiquitin ligase complex. PMID: 28007894
  2. Results suggest that STYX is a pseudophosphatase that uses the 'competitor' and 'anchor' mode of action to exert its biologic roles. [review] PMID: 28408485
  3. results identify STYX as an important regulator of ERK1/2 signaling critical for cell migration PMID: 23847209
Subcellular Location Nucleus, Cytoplasm, cytosol
Protein Families Protein-tyrosine phosphatase family, Non-receptor class subfamily
Database Links

HGNC: 11447

OMIM: 615814

KEGG: hsa:6815

STRING: 9606.ENSP00000346599

UniGene: Hs.364980

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