SUGCT Antibody

Code CSB-PA004146GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SUGCT
Alternative Names
SUGCT antibody; C7orf10 antibody; DERP13 antibody; Succinate--hydroxymethylglutarate CoA-transferase antibody; EC 2.8.3.13 antibody; Dermal papilla-derived protein 13 antibody; SuccinylCoA:glutarate-CoA transferase antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human C7orf10
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.
Gene References into Functions
  1. Chromosome microarray analysis showed a 125kb homozygous pathogenic deletion, which includes genes MPLKIP and SUGCT, not described before. This is the first case described in Peru of a novel contiguous gene deletion of Trichothiodystrophy type 4 and Glutaric aciduria type 3 performed by chromosome microarray analysis. PMID: 29421601
  2. C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, which is the enzyme that converts glutarate to glutaryl-CoA PMID: 23893049
  3. Identified as a candidate disease gene for OXPHOS disorders by next-generation sequencing PMID: 22277967
  4. Geneic mapping of GA3 to chromosome 7 and identification of mutations in c7orf10 are reported. PMID: 18926513
Involvement in disease
Glutaric aciduria 3 (GA3)
Subcellular Location
Mitochondrion.
Protein Families
CaiB/BaiF CoA-transferase family
Tissue Specificity
Highly expressed in kidney. Intermediate expression in liver, skeletal muscle and pancreas. Little to no expression detected in other tissues examined.
Database Links

HGNC: 16001

OMIM: 231690

KEGG: hsa:79783

UniGene: Hs.586313

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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