SUGCT Antibody

Datasheet

Code	CSB-PA867183ESR2HU
Size	US$166
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Image	Western blot All lanes: SUGCT antibody at 16μg/ml Lane 1: Mouse skeletal muscle tissue Lane 2: Mouse liver tissue Lane 3: Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49, 48, 52, 44 kDa Observed band size: 42 kDa Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA867183ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA867183ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SUGCT Polyclonal antibody

Uniprot No.

Q9HAC7

Target Names

SUGCT

Alternative Names

SUGCT antibody; C7orf10 antibody; DERP13 antibody; Succinate--hydroxymethylglutarate CoA-transferase antibody; EC 2.8.3.13 antibody; Dermal papilla-derived protein 13 antibody; SuccinylCoA:glutarate-CoA transferase antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Succinate--hydroxymethylglutarate CoA-transferase protein (1-250AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.

Gene References into Functions

Chromosome microarray analysis showed a 125kb homozygous pathogenic deletion, which includes genes MPLKIP and SUGCT, not described before. This is the first case described in Peru of a novel contiguous gene deletion of Trichothiodystrophy type 4 and Glutaric aciduria type 3 performed by chromosome microarray analysis. PMID: 29421601
C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, which is the enzyme that converts glutarate to glutaryl-CoA PMID: 23893049
Identified as a candidate disease gene for OXPHOS disorders by next-generation sequencing PMID: 22277967
Geneic mapping of GA3 to chromosome 7 and identification of mutations in c7orf10 are reported. PMID: 18926513

Involvement in disease

Glutaric aciduria 3 (GA3)

Subcellular Location

Mitochondrion.

Protein Families

CaiB/BaiF CoA-transferase family

Tissue Specificity

Highly expressed in kidney. Intermediate expression in liver, skeletal muscle and pancreas. Little to no expression detected in other tissues examined.

Database Links

HGNC: 16001

OMIM: 231690

KEGG: hsa:79783

UniGene: Hs.586313

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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