SUMF2 Antibody, HRP conjugated

Code CSB-PA839844LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SUMF2 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
SUMF2 antibody; PSEC0171 antibody; UNQ1968/PRO4500 antibody; Inactive C-alpha-formylglycine-generating enzyme 2 antibody; Paralog of formylglycine-generating enzyme antibody; pFGE antibody; Sulfatase-modifying factor 2 antibody
Raised in
Species Reactivity
Recombinant Human Sulfatase-modifying factor 2 protein (26-301AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
>95%, Antigen Affinity purified & Affinity purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1.
Gene References into Functions
  1. SUMF2 interacted with IL-13 and inhibited IL-13 secretion in bronchial smooth muscle cells and lymphocytes, which was independent of IL-13 glycosylation PMID: 19739097
  2. structural analysis of human pFGE by X-ray crystallography [pFGE] PMID: 15687489
  3. pFGE (SUMF2) is the paralog of the Calpha-formylglycine-generating enzyme PMID: 15708861
  4. SUMF2 interacts with sulphatase-modifying factor 1 to regulate sulphatase activities. PMID: 15962010
  5. pFGE is retained in the ER through its C-terminal tetrapeptide PGEL, a noncanonical variant of the classic KDEL ER-retention signal. PMID: 18266766

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Subcellular Location
Endoplasmic reticulum lumen.
Protein Families
Sulfatase-modifying factor family
Tissue Specificity
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta.
Database Links

HGNC: 20415

OMIM: 607940

KEGG: hsa:25870

STRING: 9606.ENSP00000341938

UniGene: Hs.279696

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