SYCP1 Antibody

Datasheet

Code	CSB-PA225456
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA225456(SYCP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q15431

Target Names

SYCP1

Alternative Names

Cancer/testis antigen 8 antibody; CT8 antibody; HOM TES 14 antibody; MGC104417 antibody; SCP 1 antibody; SCP-1 antibody; SCP1 antibody; SYCP 1 antibody; Sycp1 antibody; SYCP1_HUMAN antibody; Synaptonemal complex protein 1 antibody; Testicular tissue protein Li 191 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human SYCP1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.

Gene References into Functions

Crystal structure of C-terminal coiled-coil domain of SYCP1 reveals non-canonical anti-parallel dimeric structure of transverse filament at the synaptonemal complex. PMID: 27548613
crystal structure of the middle part of the human synaptonemal complex protein 1 coiled-coil domain PMID: 26323297
SYCP1, cTAGE1, and GTSF1 are expressed in cutaneous T-cell lymphoma, but not in normal skin or benign inflammatory dermatoses. PMID: 24850846
Cancer-Testis Antigen SCP-1 mRNA is expressed in some nasopharyngeal carcinoma. PMID: 17608150
an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4+ T cells PMID: 16030183

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Subcellular Location

Nucleus. Chromosome. Chromosome, centromere.

Tissue Specificity

Testis.

Database Links

HGNC: 11487

OMIM: 602162

KEGG: hsa:6847

STRING: 9606.ENSP00000358531

UniGene: Hs.112743

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Cell markers

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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