SYCP1 Antibody

Code CSB-PA225456
Size US$299
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA225456(SYCP1 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No. Q15431
Target Names SYCP1
Alternative Names Cancer/testis antigen 8 antibody; CT8 antibody; HOM TES 14 antibody; MGC104417 antibody; SCP 1 antibody; SCP-1 antibody; SCP1 antibody; SYCP 1 antibody; Sycp1 antibody; SYCP1_HUMAN antibody; Synaptonemal complex protein 1 antibody; Testicular tissue protein Li 191 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Synthetic peptide of Human SYCP1
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method Antigen affinity purification
Concentration It differs from different batches. Please contact us to confirm it.
Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form Liquid
Tested Applications ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
IHC 1:25-1:100
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.
Gene References into Functions
  1. Crystal structure of C-terminal coiled-coil domain of SYCP1 reveals non-canonical anti-parallel dimeric structure of transverse filament at the synaptonemal complex. PMID: 27548613
  2. crystal structure of the middle part of the human synaptonemal complex protein 1 coiled-coil domain PMID: 26323297
  3. SYCP1, cTAGE1, and GTSF1 are expressed in cutaneous T-cell lymphoma, but not in normal skin or benign inflammatory dermatoses. PMID: 24850846
  4. Cancer-Testis Antigen SCP-1 mRNA is expressed in some nasopharyngeal carcinoma. PMID: 17608150
  5. an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4+ T cells PMID: 16030183

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Subcellular Location Nucleus, Chromosome, Chromosome, centromere
Tissue Specificity Testis.
Database Links

HGNC: 11487

OMIM: 602162

KEGG: hsa:6847

STRING: 9606.ENSP00000358531

UniGene: Hs.112743

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