SYNJ2BP Antibody, FITC conjugated

Code CSB-PA023018LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SYNJ2BP Polyclonal antibody
Uniprot No.
Target Names
SYNJ2BP
Alternative Names
SYNJ2BP antibody; OMP25 antibody; Synaptojanin-2-binding protein antibody; Mitochondrial outer membrane protein 25 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Synaptojanin-2-binding protein (1-117AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
Gene References into Functions
  1. Data found that SYNJ2BP was decreased in hepatocellular carcinoma (HCC) tissues and cell lines and provide evidence that SYNJ2BP may act as a tumor suppressor during HCC development activating DLL4 pathway. PMID: 27440153
  2. Ubiquilins are a family of chaperones for cytosolically exposed transmembrane domains and use ubiquitin to triage clients, like Omp25, for degradation via coordinated intra- and intermolecular interactions. PMID: 27345149
  3. These results suggest that ARIP2 is a putative growth-promoting factor involved in breast tumorigenesis and tumor development. PMID: 19349195
Subcellular Location
Mitochondrion outer membrane.
Database Links

HGNC: 18955

OMIM: 609411

KEGG: hsa:55333

STRING: 9606.ENSP00000256366

UniGene: Hs.443661

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