SYNJ2BP, also known as synaptojanin 2 binding protein, is an important protein. It has few well - known common aliases. This protein plays a crucial role in membrane trafficking and endocytosis. It interacts with synaptojanin 2 and participates in the regulation of phosphatidylinositol metabolism, which is closely related to the PI3K - AKT signaling pathway.
Abnormalities in SYNJ2BP have been associated with certain neurodegenerative diseases, possibly due to its effects on synaptic function. In drug development, research is in the early stage, focusing on understanding its detailed mechanism to find potential targets for treating related diseases.
SYNJ2BP Antibody (CSB-PA023018LA01HU)
Validated Data
Immunoprecipitating SYNJ2BP in Rat kidney tissue
Lane 1: Rabbit control IgG instead of CSB-PA023018LA01HU in Rat kidney tissue. For western blotting, a HRP-conjugated light chain specific antibody was used as the secondary antibody (1/50000)
Lane 2: CSB-PA023018LA01HU (6µg) + Rat kidney tissue (500µg)
Lane 3: Rat kidney tissue (20µg)
Western blot
All lanes: SYNJ2BP antibody at 3µg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: U251 whole cell lysate
Lane 3: Caco-2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 16 kDa
Observed band size: 16 kDa
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA023018LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023018LA01HU at dilution of 1:100
Western Blot
Positive WB detected in: Rat kidney tissue
All lanes: SYNJ2BP antibody at 2.8μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 16 kDa
Observed band size: 16 kDa
Immunohistochemistry analysis of human liver cancer using CSB-PA023018LA01HU at dilution of 1:100
The following SYNJ2BP reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
SYNJ2BP Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA023018GA01HU | SYNJ2BP Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
CSB-PA023018LA01HU | SYNJ2BP Antibody | Human, Rat | ELISA, WB, IHC, IP |
CSB-PA023018LB01HU | SYNJ2BP Antibody, HRP conjugated | Human | ELISA |
CSB-PA023018LC01HU | SYNJ2BP Antibody, FITC conjugated | Human |
SYNJ2BP Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP023018HU CSB-EP023018HU CSB-BP023018HU CSB-MP023018HU CSB-EP023018HU-B |
Recombinant Human Synaptojanin-2-binding protein (SYNJ2BP) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |