SYNJ2BP Antibody

Code CSB-PA023018LA01HU
Size US$166
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  • Immunoprecipitating SYNJ2BP in Rat kidney tissue
    Lane 1: Rabbit control IgG instead of CSB-PA023018LA01HU in Rat kidney tissue. For western blotting, a HRP-conjugated light chain specific antibody was used as the secondary antibody (1/50000)
    Lane 2: CSB-PA023018LA01HU (6µg) + Rat kidney tissue (500µg)
    Lane 3: Rat kidney tissue (20µg)

  • Western blot
    All lanes: SYNJ2BP antibody at 3µg/ml
    Lane 1: MCF-7 whole cell lysate
    Lane 2: U251 whole cell lysate
    Lane 3: Caco-2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 16 kDa
    Observed band size: 16 kDa

     

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA023018LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023018LA01HU at dilution of 1:100

  • Western Blot
    Positive WB detected in: Rat kidney tissue
    All lanes: SYNJ2BP antibody at 2.8μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 16 kDa
    Observed band size: 16 kDa

  • Immunohistochemistry analysis of human liver cancer using CSB-PA023018LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SYNJ2BP Polyclonal antibody
Uniprot No.
Target Names
SYNJ2BP
Alternative Names
SYNJ2BP antibody; OMP25 antibody; Synaptojanin-2-binding protein antibody; Mitochondrial outer membrane protein 25 antibody
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human Synaptojanin-2-binding protein (1-117AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SYNJ2BP Antibody (Product code: CSB-PA023018LA01HU) is Non-conjugated. For SYNJ2BP Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA023018LB01HU SYNJ2BP Antibody, HRP conjugated ELISA
FITC CSB-PA023018LC01HU SYNJ2BP Antibody, FITC conjugated
Biotin CSB-PA023018LD01HU SYNJ2BP Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IP
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IP 1:200-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
Gene References into Functions
  1. Data found that SYNJ2BP was decreased in hepatocellular carcinoma (HCC) tissues and cell lines and provide evidence that SYNJ2BP may act as a tumor suppressor during HCC development activating DLL4 pathway. PMID: 27440153
  2. Ubiquilins are a family of chaperones for cytosolically exposed transmembrane domains and use ubiquitin to triage clients, like Omp25, for degradation via coordinated intra- and intermolecular interactions. PMID: 27345149
  3. These results suggest that ARIP2 is a putative growth-promoting factor involved in breast tumorigenesis and tumor development. PMID: 19349195
Subcellular Location
Mitochondrion outer membrane.
Database Links

HGNC: 18955

OMIM: 609411

KEGG: hsa:55333

STRING: 9606.ENSP00000256366

UniGene: Hs.443661

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