SYT6 Antibody

Datasheet

Code	CSB-PA716356LA01HU
Size	US$166
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Image	Immunofluorescence staining of MCF-7 cells with CSB-PA716356LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SYT6 Polyclonal antibody

Uniprot No.

Q5T7P8

Target Names

SYT6

Alternative Names

Synaptotagmin 6 antibody; Synaptotagmin VI antibody; Synaptotagmin-6 antibody; Synaptotagmin6 antibody; SynaptotagminVI antibody; Syt 6 antibody; Syt VI antibody; SYT6 antibody; SYT6_HUMAN antibody; SytVI antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Synaptotagmin-6 protein (104-425AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SYT6 Antibody (Product code: CSB-PA716356LA01HU) is Non-conjugated. For SYT6 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA716356LB01HU	SYT6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA716356LC01HU	SYT6 Antibody, FITC conjugated
Biotin	CSB-PA716356LD01HU	SYT6 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. May mediate Ca(2+)-regulation of exocytosis in acrosomal reaction in sperm.

Gene References into Functions

synaptotagmin must be dephosphorylated at a specific window of time and phosphorylated synaptotagmin has an active role at early stages of the acrosomal exocytosis. PMID: 20551332
Acrosomal exocytosis is regulated through the PKC-mediated phosphorylation of conserved threonines in the polybasic regions of synaptotagmin VI. PMID: 16111671
SYT6 is hypermethylated in renal cell carcinoma. PMID: 18639284

Subcellular Location

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein.; [Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.

Protein Families

Synaptotagmin family

Database Links

HGNC: 18638

OMIM: 607718

KEGG: hsa:148281

STRING: 9606.ENSP00000358559

UniGene: Hs.370963

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Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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