TAF7L Antibody, FITC conjugated

Code CSB-PA688972LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAF7L Polyclonal antibody
Uniprot No.
Target Names
TAF7L
Alternative Names
TAF7L antibody; TAF2Q antibody; Transcription initiation factor TFIID subunit 7-like antibody; Cancer/testis antigen 40 antibody; CT40 antibody; RNA polymerase II TBP-associated factor subunit Q antibody; TATA box-binding protein-associated factor 50 kDa antibody; Transcription initiation factor TFIID 50 kDa subunit antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription initiation factor TFIID subunit 7-like protein (1-98AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis.
Gene References into Functions
  1. Over-expression of TAF7L was observed in breast tumor cell lines. PMID: 26107214
  2. Frameshift mutations of TAF7L gene is associated with stomach and colorectal cancers. PMID: 25098277
  3. expression of AURKC, OIP5, PIWIL2 and TAF7L differed between patients with Acute myeloid leukemia, myelodysplastic syndrome and healthy controls in a gender-dependent manner PMID: 23292864
  4. TAF7L gene polymorphisms were found in male infertility patients and normal controls. PMID: 16597641
  5. The sequence variant in exon 13 of the TAF7L gene located on the X chromosome may represent a risk factor for spermatogenic failure. PMID: 17714218

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Subcellular Location
Nucleus. Cytoplasm.
Protein Families
TAF7 family
Tissue Specificity
Testis-specific.
Database Links

HGNC: 11548

OMIM: 300314

KEGG: hsa:54457

STRING: 9606.ENSP00000361998

UniGene: Hs.223806

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