TAF7L Antibody, HRP conjugated

Code CSB-PA688972LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAF7L Polyclonal antibody
Uniprot No.
Target Names
TAF7L
Alternative Names
TAF7L antibody; TAF2Q antibody; Transcription initiation factor TFIID subunit 7-like antibody; Cancer/testis antigen 40 antibody; CT40 antibody; RNA polymerase II TBP-associated factor subunit Q antibody; TATA box-binding protein-associated factor 50 kDa antibody; Transcription initiation factor TFIID 50 kDa subunit antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription initiation factor TFIID subunit 7-like protein (1-98AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Probably functions as a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis.
Gene References into Functions
  1. Over-expression of TAF7L was observed in breast tumor cell lines. PMID: 26107214
  2. Frameshift mutations of TAF7L gene is associated with stomach and colorectal cancers. PMID: 25098277
  3. expression of AURKC, OIP5, PIWIL2 and TAF7L differed between patients with Acute myeloid leukemia, myelodysplastic syndrome and healthy controls in a gender-dependent manner PMID: 23292864
  4. TAF7L gene polymorphisms were found in male infertility patients and normal controls. PMID: 16597641
  5. The sequence variant in exon 13 of the TAF7L gene located on the X chromosome may represent a risk factor for spermatogenic failure. PMID: 17714218

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Subcellular Location
Nucleus. Cytoplasm.
Protein Families
TAF7 family
Tissue Specificity
Testis-specific.
Database Links

HGNC: 11548

OMIM: 300314

KEGG: hsa:54457

STRING: 9606.ENSP00000361998

UniGene: Hs.223806

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