TIMMDC1 Antibody

Code CSB-PA885685LA01HU
Size US$166
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Image
  • Western Blot
    Positive WB detected in: A375 whole cell lysate, Mouse heart tissue
    All lanes: TIMMDC1 antibody at 2.9μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 33 kDa
    Observed band size: 33 kDa
  • IHC image of CSB-PA885685LA01HU diluted at 1:100 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TIMMDC1 Polyclonal antibody
Uniprot No.
Target Names
TIMMDC1
Alternative Names
TIMMDC1; C3orf1; UNQ247/PRO284; Complex I assembly factor TIMMDC1, mitochondrial; Protein M5-14; Translocase of inner mitochondrial membrane domain-containing protein 1; TIMM domain containing-protein 1
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (1-71AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TIMMDC1 Antibody (Product code: CSB-PA885685LA01HU) is Non-conjugated. For TIMMDC1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA885685LB01HU TIMMDC1 Antibody, HRP conjugated ELISA
FITC CSB-PA885685LC01HU TIMMDC1 Antibody, FITC conjugated
Biotin CSB-PA885685LD01HU TIMMDC1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews
Average Rating:
5.0 - 1 reviews

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Applications : WB

Sample type: Mouse Heart tissue

Review: Expression of hub genes was measured by qRT- PCR and Western blotting. Scale bar: 20mm (A); mean–SEM value of at least six mice per group.

By Anonymous

Target Background

Function
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I.
Gene References into Functions
  1. Cell-cycle arrest genes such as CCNG2 and PTEN as well as genes involved in cell migration inhibition, such as TIMP3 and COL3A1, were upregulated after C3orf1 depletion in 95D cells. PMID: 25391042
  2. Quantitative proteomics demonstrated a role for TIMMDC1 in assembly of membrane-embedded and soluble arms of the complex. PMID: 24344204
Subcellular Location
Mitochondrion membrane; Multi-pass membrane protein.
Protein Families
Tim17/Tim22/Tim23 family
Tissue Specificity
Generalized expression enhanced in heart and skeletal muscle.
Database Links

HGNC: 1321

OMIM: 615534

KEGG: hsa:51300

STRING: 9606.ENSP00000418803

UniGene: Hs.477287

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