TIMMDC1 Antibody

Code CSB-PA885685LA01HU
Size US$299
Image
  • Western Blot
    Positive WB detected in: A375 whole cell lysate, Mouse heart tissue
    All lanes: TIMMDC1 antibody at 2.9μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 33 kDa
    Observed band size: 33 kDa

  • IHC image of CSB-PA885685LA01HU diluted at 1:100 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) TIMMDC1 Polyclonal antibody
Uniprot No. Q9NPL8
Target Names TIMMDC1
Alternative Names C3orf1 antibody; M5 14 protein antibody; Protein M5-14 antibody; TIDC1_HUMAN antibody; TIMMDC 1 antibody; timmdc1 antibody; Translocase of inner mitochondrial membrane domain containing 1 antibody; Translocase of inner mitochondrial membrane domain containing protein 1 antibody; Translocase of inner mitochondrial membrane domain-containing protein 1 antibody; Transmembrane protein C3orf1 antibody
Raised in Rabbit
Species Reactivity Human, Mouse
Immunogen Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (444-585AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Citations

Potentially Critical Roles of NDUFB5, TIMMDC1, and VDAC3 in the Progression of Septic Cardiomyopathy Through Integrated Bioinformatics Analysis. Kang K, et al,Dna and Cell Biology,2019

Sample type: Heart tissue
Sample species: Mouse
Application:WB
Review: Expression of hub genes was measured by qRT- PCR and Western blotting. Scale bar: 20mm (A); mean–SEM value of at least six mice per group.
PMID: 31794266

Target Data

Function Chaperone protein involved in the assembly of the mitochondrial NADH
Gene References into Functions
  1. Cell-cycle arrest genes such as CCNG2 and PTEN as well as genes involved in cell migration inhibition, such as TIMP3 and COL3A1, were upregulated after C3orf1 depletion in 95D cells. PMID: 25391042
  2. Quantitative proteomics demonstrated a role for TIMMDC1 in assembly of membrane-embedded and soluble arms of the complex. PMID: 24344204
Subcellular Location Mitochondrion membrane, Multi-pass membrane protein
Protein Families Tim17/Tim22/Tim23 family
Tissue Specificity Generalized expression enhanced in heart and skeletal muscle.
Database Links

HGNC: 1321

OMIM: 615534

KEGG: hsa:51300

STRING: 9606.ENSP00000418803

UniGene: Hs.477287

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