TIMMDC1 Antibody

Datasheet

Citations (1)

Code	CSB-PA885685LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: A375 whole cell lysate, Mouse heart tissue All lanes: TIMMDC1 antibody at 2.9μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 33 kDa Observed band size: 33 kDa IHC image of CSB-PA885685LA01HU diluted at 1:100 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Product Details
Citations
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TIMMDC1 Polyclonal antibody

Uniprot No.

Q9NPL8

Target Names

TIMMDC1

Alternative Names

TIMMDC1; C3orf1; UNQ247/PRO284; Complex I assembly factor TIMMDC1, mitochondrial; Protein M5-14; Translocase of inner mitochondrial membrane domain-containing protein 1; TIMM domain containing-protein 1

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (1-71AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TIMMDC1 Antibody (Product code: CSB-PA885685LA01HU) is Non-conjugated. For TIMMDC1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA885685LB01HU	TIMMDC1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA885685LC01HU	TIMMDC1 Antibody, FITC conjugated
Biotin	CSB-PA885685LD01HU	TIMMDC1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

Potentially Critical Roles of NDUFB5, TIMMDC1, and VDAC3 in the Progression of Septic Cardiomyopathy Through Integrated Bioinformatics Analysis Kang K, et al,Dna and Cell Biology,2019

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

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Applications : WB

Sample type: Mouse Heart tissue

Review: Expression of hub genes was measured by qRT- PCR and Western blotting. Scale bar: 20mm (A); mean–SEM value of at least six mice per group.

By Anonymous

Target Background

Function

Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I.

Gene References into Functions

Cell-cycle arrest genes such as CCNG2 and PTEN as well as genes involved in cell migration inhibition, such as TIMP3 and COL3A1, were upregulated after C3orf1 depletion in 95D cells. PMID: 25391042
Quantitative proteomics demonstrated a role for TIMMDC1 in assembly of membrane-embedded and soluble arms of the complex. PMID: 24344204

Subcellular Location

Mitochondrion membrane; Multi-pass membrane protein.

Protein Families

Tim17/Tim22/Tim23 family

Tissue Specificity

Generalized expression enhanced in heart and skeletal muscle.

Database Links

HGNC: 1321

OMIM: 615534

KEGG: hsa:51300

STRING: 9606.ENSP00000418803

UniGene: Hs.477287

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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