TIMMDC1 Antibody, FITC conjugated

Code CSB-PA885685LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TIMMDC1 Polyclonal antibody
Uniprot No.
Target Names
TIMMDC1
Alternative Names
TIMMDC1; C3orf1; UNQ247/PRO284; Complex I assembly factor TIMMDC1, mitochondrial; Protein M5-14; Translocase of inner mitochondrial membrane domain-containing protein 1; TIMM domain containing-protein 1
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human E3 ubiquitin-protein ligase UHRF2 protein (444-585AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Participates in constructing the membrane arm of complex I.
Gene References into Functions
  1. Cell-cycle arrest genes such as CCNG2 and PTEN as well as genes involved in cell migration inhibition, such as TIMP3 and COL3A1, were upregulated after C3orf1 depletion in 95D cells. PMID: 25391042
  2. Quantitative proteomics demonstrated a role for TIMMDC1 in assembly of membrane-embedded and soluble arms of the complex. PMID: 24344204
Subcellular Location
Mitochondrion membrane; Multi-pass membrane protein.
Protein Families
Tim17/Tim22/Tim23 family
Tissue Specificity
Generalized expression enhanced in heart and skeletal muscle.
Database Links

HGNC: 1321

OMIM: 615534

KEGG: hsa:51300

STRING: 9606.ENSP00000418803

UniGene: Hs.477287

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