TMEM176B Antibody

Datasheet

Code	CSB-PA023758LA01HU
Size	US$166
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Image	Western blot All lanes: TMEM176B antibody at 8µg/ml + Human placenta tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 30, 26 kDa Observed band size: 30 kDa Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA023758LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA023758LA01HU at dilution of 1:100 Immunofluorescent analysis of LO2 cells using CSB-PA023758LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
Citations
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TMEM176B Polyclonal antibody

Uniprot No.

Q3YBM2

Target Names

TMEM176B

Alternative Names

TMEM176B; LR8; Transmembrane protein 176B; Protein LR8

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Transmembrane protein 176B protein (1-64AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TMEM176B Antibody (Product code: CSB-PA023758LA01HU) is Non-conjugated. For TMEM176B Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA023758LB01HU	TMEM176B Antibody, HRP conjugated	ELISA
FITC	CSB-PA023758LC01HU	TMEM176B Antibody, FITC conjugated
Biotin	CSB-PA023758LD01HU	TMEM176B Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

To produce the TMEM176B antibody, a rabbit was first immunized with the recombinant human transmembrane protein 176B (1-64aa). Following this, the rabbit serum was collected and the antibody was isolated and purified through protein G affinity chromatography.

The resulting antibody showed high purity levels of up to 95% and displayed reactivity solely with human TMEM176B protein. Quality verification tests were conducted on the rabbit anti-human TMEM176B polyclonal antibody, including ELISA, WB, IHC, and IF, confirming its suitability for use in various applications.

Citations

Single-cell mRNA-regulation analysis reveals cell type-specific mechanisms of type 2 diabetes J Martinez-Lopez,bioRxiv,2023

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

Submit a Review here

Applications : Immunohistochemistry

Sample type: tissues

Review: TMEM176B protein is expressed in human beta cells.

By Anonymous

Target Background

Function

May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells.

Gene References into Functions

Study characterized Tmem176a and b expression in RORgamma t+ lymphocytes at transcriptional and protein levels and present evidence that both genes exert a redundant ion channel function related to a colocalisation in close proximity to the Golgi apparatus. PMID: 27009467
human TMEM176A and 176B protein levels are significantly elevated in lymphoma, but not in normal tissues PMID: 22244448

Subcellular Location

Nucleus membrane; Multi-pass membrane protein.

Protein Families

TMEM176 family

Tissue Specificity

Expressed in lung and dermal fibroblasts.

Database Links

HGNC: 29596

OMIM: 610385

KEGG: hsa:28959

STRING: 9606.ENSP00000318409

UniGene: Hs.647090

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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