TMEM176B

TMEM176B, also known as Transmembrane Protein 176B, functions as a regulator in various cellular processes. It has several common aliases, though specific ones may vary in different literature. Mechanistically, it is involved in modulating signal transduction pathways.
TMEM176B is associated with the NF - κB signaling pathway, which plays a key role in inflammation and immune response. It has been linked to certain autoimmune diseases and cancers. Currently, research on drugs targeting TMEM176B is in the early stages, with efforts focused on understanding its full potential for disease treatment.

Popular Product:

TMEM176B Antibody (CSB-PA023758LA01HU)

Validated Data

Western Blot
Positive WB detected in: THP-1 whole cell lysate(30µg), SY5Y whole cell lysate(30µg), Hela whole cell lysate(30µg), K562 whole cell lysate(30µg)
All lanes: TMEM176B antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/20000 dilution
Predicted band size: 30,26 kDa
Observed band size: 30 kDa
Exposure time：120s

Immunofluorescence staining of Hela cell with CSB-PA023758LA01HU at 1:30, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and and permeated by 0.2% TritonX-100 for 15 min. Then 10% normal goat serum to block non-specific protein-protein interactions . The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Immunofluorescence staining of Hela cell with 5% goat serum, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

The following TMEM176B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TMEM176B Antibodies

TMEM176B Proteins

TMEM176B Antibodies

TMEM176B Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA023758GA01HU	TMEM176B Antibody	Human	ELISA,WB
CSB-PA023758LA01HU	TMEM176B Antibody	Human	ELISA, WB, IF
CSB-PA023758LC01HU	TMEM176B Antibody, FITC conjugated	Human
CSB-PA023758LB01HU	TMEM176B Antibody, HRP conjugated	Human	ELISA

TMEM176B Proteins

TMEM176B Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-CF023758HU	Recombinant Human Transmembrane protein 176B (TMEM176B)	in vitro E.coli expression system
CSB-YP023758HU1 CSB-EP023758HU1 CSB-BP023758HU1 CSB-MP023758HU1 CSB-EP023758HU1-B	Recombinant Human Transmembrane protein 176B (TMEM176B), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

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