TMEM2 Antibody, FITC conjugated

Datasheet
Code CSB-PA23279C0Rb
Size US$299
Uniprot No. Q9UHN6
Protocols ELISA Protocol
Immunogen Recombinant Human Cell surface hyaluronidase protein (734-866AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments (PubMed:28246172). Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling (By similarity). Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate (PubMed:28246172).
Form Liquid
Conjugate FITC
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Cell surface hyaluronidase (EC 3.2.1.35) (Transmembrane protein 2), TMEM2, KIAA1412
Immunogen Species Homo sapiens (Human)
Research Area Cell Biology
Target Names TMEM2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments
Subcellular Location Cell membrane, Single-pass type II membrane protein
Protein Families TMEM2 family
Tissue Specificity Widely expressed.
Database Links

HGNC: 11869

OMIM: 605835

KEGG: hsa:23670

STRING: 9606.ENSP00000366243

UniGene: Hs.494146

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