TMEM30B Antibody

Code CSB-PA194152
Size US$297
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  • Western blot analysis of extracts from K562 cells, using TMEM30B antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TMEM30B Polyclonal antibody
Uniprot No.
Target Names
TMEM30B
Alternative Names
TMEM30B; CDC50B; Cell cycle control protein 50B; P4-ATPase flippase complex beta subunit TMEM30B; Transmembrane protein 30B
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human TMEM30B.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane.
Gene References into Functions
  1. Downregulation of TMEM30B is associated with recurrence in meningiomas. PMID: 20685720
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
CDC50/LEM3 family
Database Links

HGNC: 27254

OMIM: 611029

KEGG: hsa:161291

STRING: 9606.ENSP00000347930

UniGene: Hs.146180

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