TNN Antibody

Datasheet
Code CSB-PA775994
Size US$299
Uniprot No. Q9UQP3
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA775994(TNN Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA775994(TNN Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Immunogen Synthetic peptide of Human TNN
Raised in Rabbit
Species Reactivity Human,Mouse
Tested Applications ELISA,IHC;ELISA:1:3000-1:10000,IHC:1:50-1:200
Relevance This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias tenascin N
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Target Names TNN
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Extracellular matrix protein that seems to be a ligand for ITGA8
Subcellular Location Secreted, extracellular space, extracellular matrix
Protein Families Tenascin family
Tissue Specificity Not detected in normal adult mammary tissues or brain but expressed in most breast tumors and brain tumors, such as glioblastomas, astrocytomas and oligodendrogliomas, tested (PubMed:17909022, PubMed:19884327). In brain tumors, detected around the endothe
Database Links

HGNC: 22942

OMIM: 617472

KEGG: hsa:63923

STRING: 9606.ENSP00000239462

UniGene: Hs.156369

Pathway PI3K-Akt signaling pathway
Focal adhesion

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