TRA2A Antibody

Code CSB-PA004320
Size US$100
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  • Western Blot analysis of HuvEc cells using Tra-2α Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
TRA2A
Alternative Names
AWMS1 antibody; HSU53209 antibody; htra-2 alpha antibody; Putative MAPK activating protein PM24 antibody; TRA 2 alpha antibody; TRA 2A antibody; TRA-2 alpha antibody; TRA2 alpha antibody; TRA2-alpha antibody; TRA2A antibody; TRA2A_HUMAN antibody; Tra2alpha antibody; Transformer 2 alpha antibody; Transformer 2 protein homolog antibody; Transformer-2 protein homolog A antibody; Transformer-2 protein homolog alpha antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of Human Tra-2α.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing.
Gene References into Functions
  1. our findings suggest that paclitaxel targets the TRA2A-RSRC2 splicing pathway, and deregulated TRA2A and RSRC2 expression may confer paclitaxel resistance. In addition, our study demonstrates that expression of TRA2A in conjunction with RSRC2 may provide valuable molecular biomarker evidence for triple-negative breast cancer (TNBC)clinical treatment decisions and patient outcome PMID: 28416606
  2. Overexpression of either Tra2alpha or Tra2beta results in a marked reduction in HIV-1 Gag/ Env expression. PMID: 25970345
  3. findings show the inclusion of both HIV-1 exon 3 and vpr mRNA processing is promoted by an exonic splicing enhancer (ESEvpr) localized between exonic splicing silencer ESSV and 5'ss D3; the ESEvpr sequence was found to be bound by members of the Tra2 protein family PMID: 23255807
  4. Expression of tumor-promoting Cyr61 is regulated by hTRA2-beta1 and acidosis. PMID: 21447598
Subcellular Location
Nucleus.
Protein Families
Splicing factor SR family
Database Links

HGNC: 16645

OMIM: 602718

KEGG: hsa:29896

STRING: 9606.ENSP00000297071

UniGene: Hs.445652

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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