TREH Antibody

1. these results indicate that trehalose has anti-apoptotic effects through the suppression of oxidative stress-induced mitochondrial injury and ER stress which is dependent on the promotion of autophagic flux and the induction of selective autophagy PMID: 28981117
2. In conclusion, we identified four novel loci (TGFA, PIK3R1, FGFR3 and TREH) and confirmed two loci known to be associated with cartilage thickness.The identified associations were not caused by rare exonic variants. This is the first report linking TGFA to human Osteoarthritis, which may serve as a new target for future therapies. PMID: 27701424
3. results suggest a significant association between the RETL1, TREH, and PHLDB1 genes and GBM development in the Han Chinese population PMID: 26156397
4. variants in TREH control trehalase activity, and although one of these variants is also reproducibly associated with T2D, it is likely that the effect of the SNP on risk of T2D occurs by a mechanism different than affecting trehalase activity. PMID: 23468175
5. we found three protective alleles for glioma patients, including the allele ''T'' of rs17748 in the TREH gene by recessive model (OR, 0.48; 95% CI, 0.23-1.01; P = 0.05) analysis PMID: 22369735
6. These results suggest that TREH acts as a stress-response protein in the kidney rather than involved in utilization of exogenous trehalose. PMID: 19126402

Show More

Hide All

HGNC: 12266

OMIM: 275360

KEGG: hsa:11181

STRING: 9606.ENSP00000264029

UniGene: Hs.129712