TRMT1 Antibody

Datasheet

Code	CSB-PA024536GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9NXH9

Target Names

TRMT1

Alternative Names

2)G26)dimethyltransferase antibody; 2-dimethylguanosine-26 methyltransferase antibody; FLJ20244 antibody; N(2) N(2) dimethylguanosine tRNA methyltransferase antibody; N(2)-N(2)) methyltransferase antibody; TRM 1 antibody; TRM1 tRNA methyltransferase 1 homolog antibody; TRM1_HUMAN antibody; TRMT 1 antibody; Trmt1 antibody; tRNA (guanine(26)-N(2))-dimethyltransferase antibody; tRNA 2 2 dimethylguanosine 26 methyltransferase antibody; tRNA 2 antibody; tRNA(guanine 26 N(2) N(2)) methyltransferase antibody; tRNA(guanine-26 antibody; tRNA(m(2 2)G26)dimethyltransferase antibody; tRNA(m(2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human TRMT1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.

Gene References into Functions

Results uncover a biological role for TRMT1-catalyzed tRNA modification in redox metabolism and show that individuals with TRMT1-associated ID are likely to have major perturbations in cellular homeostasis due to the lack of m2,2G modifications. PMID: 28784718
a missense variant was found in GRM1 gene, while in the second family, a frameshift alteration was identified in TRMT1, both of which were found to co-segregate with the intellectual disability. PMID: 26308914

Protein Families

Class I-like SAM-binding methyltransferase superfamily, Trm1 family

Database Links

HGNC: 25980

OMIM: 611669

KEGG: hsa:55621

STRING: 9606.ENSP00000350352

UniGene: Hs.515169

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Virus Infection Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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