TSGA10 Antibody

Code CSB-PA863172LA01HU
Size US$166
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  • Western blot
    All lanes: TSGA10 antibody at 1.5µg/ml + U251 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 82, 35 kDa
    Observed band size: 82 kDa

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA863172LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA863172LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TSGA10 Polyclonal antibody
Uniprot No.
Target Names
TSGA10
Alternative Names
Cancer/testis antigen 79 antibody; CEP4L antibody; CT79 antibody; Predicted testis protein antibody; Testis development protein NYD-SP7 antibody; Testis-specific gene 10 protein antibody; Testis-specific protein 10 antibody; TSG10_HUMAN antibody; Tsga10 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Testis-specific gene 10 protein (1-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TSGA10 Antibody (Product code: CSB-PA863172LA01HU) is Non-conjugated. For TSGA10 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA863172LB01HU TSGA10 Antibody, HRP conjugated ELISA
FITC CSB-PA863172LC01HU TSGA10 Antibody, FITC conjugated
Biotin CSB-PA863172LD01HU TSGA10 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in spermatogenesis. When overexpressed, prevents nuclear localization of HIF1A.
Gene References into Functions
  1. TSGA10 tends to express variants with shorter 5'UTR. PMID: 28739310
  2. Overexpression of TSGA10 would induce disruption of HIF-1alpha axis and exert potent inhibitory effects on tumor angiogenesis and metastasis. PMID: 26573430
  3. Report role for mir-577/TSGA10 axis in regulation esophageal squamous cell carcinoma progression. PMID: 24294352
  4. TSGA10 should be considered as an autoantigen in a subset of autoimmune polyendocrine syndrome type 1 patients and also in a minority of systemic lupus erythematosus patients PMID: 21198756
  5. TSGA10 could influence the function of antigen presenting cells via its interaction with cytoskeletal proteins such as vimentin PMID: 20797700
  6. over-expressed in 4 of 20 hepatocellular carcinomas (HCC), 1 of 20 colon cancers, 7 of 20 ovarian cancers, 3 of 20 prostate cancers, 1 of 21 malignant melanomas, and 8 of 21 bladder cancers PMID: 15107545
  7. The RT-PCR of TSGA10 expression may help in detection of residual clonal cells leading to early diagnosis and better prognostic qualification of the acute lymphoblastic leukemia. PMID: 16406020
  8. TSGA10 is target of immune reactions in Autoimmune polyendocrine syndrome type 1 (APS1). PMID: 18000009

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Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein Families
CEP135/TSGA10 family
Tissue Specificity
Expressed in the testis, in spermatozoa (at protein level). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach.
Database Links

HGNC: 14927

OMIM: 607166

KEGG: hsa:80705

STRING: 9606.ENSP00000347161

UniGene: Hs.120267

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